This information was kindly shared with us by Arthritis Australia. It is current as of 1 August 2024.

Earlier this year Bristol Myers Squibb (BMS), the manufacturer of abatacept (Orencia®), established restrictions in the supply of this biologic medication due to global supply chain issues. Abatacept is used to treat some forms of autoimmune arthritis and many patients had to switch to an alternative treatment or extend the period between their doses to help manage their condition during the shortage.

Thankfully, BMS has announced an improved supply situation for abatacept. The following changes are effective as of August 1, 2024.

  • Improved Supply: BMS has received approximately 16 weeks’ worth of abatacept ClickJect® autoinjector ahead of schedule, which is expected to meet normal demand.
  • Orencia® Stock Hypercare Plan (OSHP) Form No Longer Required: From August 1, prescribers will no longer need to complete an OSHP form for patients requiring abatacept.
  • Patient Switching: Patients who had been switched to an alternative biological or targeted synthetic disease-modifying antirheumatic drug (b/tsDMARD) during the shortage may be switched back to abatacept if clinically appropriate.
  • Dosing Adjustments: Patients whose dosing intervals were increased during the shortage may return to their previous dose if clinically appropriate.
  • New Patients: Both subcutaneous (SC) and intravenous (IV) abatacept can now be prescribed to new patients.
  • Serious Scarcity Substitution Instrument (SSSI): The SSSI will remain in effect until October 31, 2024. This allows pharmacists to substitute the abatacept ClickJect® autoinjector for the pre-filled syringe without a new prescription.
  • Pre-filled Syringe Supply: The next shipment of abatacept pre-filled syringes is expected in late September.

It’s important to note that while the supply situation has improved, patients should consult with their healthcare providers regarding any changes to their treatment regimen.

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